115 research outputs found

    Rhythmus und Microtiming in Reggae- und Dancehall-Riddims : zur Analyse stilspezifischer Gestaltungsweisen und Entwicklungslinien

    Get PDF
    Although various approaches to the analysis of popular music have been developed over the years, the lack of reggae and dancehall in musicological research is still apparent as is the study of groove in different musical genres. This paper proposes some possibilities to describe the specific interdependencies of rhythm and microtiming in reggae and dancehall music. In order to illustrate these stylistic features and their historical development six well known riddims ranging from late 1960s Roots Reggae to modern dancehall are analyzed and compared using transcriptions as well as spectrograms

    HOW VIRGINIA DAIRYMEN CAN MANAGE PRICE RISK

    Get PDF
    Livestock Production/Industries,

    Interstellar Sonic and Alfv\'enic Mach Numbers and the Tsallis Distribution

    Full text link
    In an effort to characterize the Mach numbers of ISM magnetohydrodynamic (MHD) turbulence, we study the probability distribution functions (PDFs) of patial increments of density, velocity, and magnetic field for fourteen ideal isothermal MHD simulations at resolution 512^3. In particular, we fit the PDFs using the Tsallis function and study the dependency of fit parameters on the compressibility and magnetization of the gas. We find that the Tsallis function fits PDFs of MHD turbulence well, with fit parameters showing sensitivities to the sonic and Alfven Mach numbers. For 3D density, column density, and position-position-velocity (PPV) data we find that the amplitude and width of the PDFs shows a dependency on the sonic Mach number. We also find the width of the PDF is sensitive to global Alfvenic Mach number especially in cases where the sonic number is high. These dependencies are also found for mock observational cases, where cloud-like boundary conditions, smoothing, and noise are introduced. The ability of Tsallis statistics to characterize sonic and Alfvenic Mach numbers of simulated ISM turbulence point to it being a useful tool in the analysis of the observed ISM, especially when used simultaneously with other statistical techniques.Comment: 20 pages, 16 figures, ApJ submitte

    Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response

    Get PDF
    Insulin and insulin-like signaling regulates a broad spectrum of growth and metabolic responses to a variety of internal and environmental stimuli. For example, the inhibition of insulin-like signaling in C. elegans mediates its response to both osmotic stress and starvation. We report that in response to osmotic stress the cytosolic sulfotransferase SSU-1 antagonizes insulin-like signaling and promotes developmental arrest. Both SSU-1 and the DAF-16 FOXO transcription factor, which is activated when insulin signaling is low, are needed to drive specific responses to reduced insulin-like signaling. We demonstrate that SSU-1 functions in a single pair of sensory neurons to control intercellular signaling via the nuclear hormone receptor NHR-1 and promote both the specific transcriptional response to osmotic stress and altered lysophosphatidylcholine metabolism. Our results show the requirement of a sulfotransferase–nuclear hormone receptor neurohormonal signaling pathway for some but not all consequences of reduced insulin-like signaling.National Center for Research Resources (U.S.)National Institutes of Health (U.S.) (grant GM024663)National Science Foundation (U.S.) (grant 1122374)University of Cambridge. Centre for Trophoblast Research (Next Generation Fellowship)National Institutes of Health (U.S.) (grant GM117408

    The Relevance of Digital Sharing Business Models for Sustainability

    Full text link
    There is a growing discussion about the "Digital Sharing Economy" (DSE). The pervasiveness of digital platforms and the growing interest in a sharing (rather than ownership) style of consumption have allowed for sharing practices to scale up and become a widespread phenomenon. Digital sharing platforms offer a wide variety of services which appear to be more affordable, efficient, and accessible than their conventional counterparts, making them more attractive in the eyes of consumers. The DSE has manifested itself most remarkably in consumer-to-consumer (C2C) and business-to-consumer (B2C) sharing models. New business models have been created to capture and offer the values driving the emerging sharing trend. The innovative, digitally enabled mode of providing access to resources as a service in the DSE has changed consumption patterns both at micro level, as a change in individual lifestyles, and at macro level, manifested in a transformation of socio-economic structures. These ongoing changes may have both positive and negative implications for society from a sustainability perspective. Recognising that the (potential and actual) impacts of sharing platforms on sustainability have not been studied in a systematic way yet, the present paper aims to develop a systematic insight into this interaction by focusing on the business models emerging around sharing platforms as a central starting point. To achieve this, we use a typology of business models that recognizes the affordances and key attributes of sharing in the DSE. The typology covers both C2C and B2C models of sharing. Based on this typology, we discuss the implications of each type of sharing model for sustainability by asking two central questions: How may the given type of sharing affect resource consumption? And what will be the potential impacts on social practices and structures? We hope that the present study can serve as a guideline for assessing the sustainability impacts of sharing platforms -- either already operating in the market or envisaged. By highlighting the aspects most relevant from a sustainability point of view, we expect to contribute to an evolution of the DSE business models towards sustainable development

    The orbits of the quadruple star system 88 Tau A from PHASES differential astrometry and radial velocity

    Get PDF
    We have used high precision differential astrometry from the Palomar High-precision Astrometric Search for Exoplanet Systems (PHASES) project and radial velocity measurements covering a time-span of 20 years to determine the orbital parameters of the 88 Tau A system. 88 Tau is a complex hierarchical multiple system comprising a total of six stars; we have studied the brightest 4, consisting of two short-period pairs orbiting each other with an 18-year period. We present the first orbital solution for one of the short-period pairs, and determine the masses of the components and distance to the system to the level of a few percent. In addition, our astrometric measurements allow us to make the first determination of the mutual inclinations of the orbits. We find that the sub-systems are not coplanar.Comment: Corrected Author Ordering; 12 Pages, Accepted for publication in Ap

    Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells

    Get PDF
    The integrin LFA-1 (CD11a/CD18) plays a critical role in the interaction of T cells with antigen presenting cells (APCs) to promote lymphocyte differentiation and proliferation. This integrin can be present either in a closed or in an open active conformation and its activation upon T-cell receptor (TCR) stimulation is a critical step to allow interaction with APCs. In this study we demonstrate that the serine/threonine kinase Ndr2 is critically involved in the initiation of TCR-mediated LFA-1 activation (open conformation) in T cells. Ndr2 itself becomes activated upon TCR stimulation and phosphorylates the intracellular integrin binding partner Filamin A (FLNa) at serine 2152. This phosphorylation promotes the dissociation of FLNa from LFA-1, allowing for a subsequent association of Talin and Kindlin-3 which both stabilize the open conformation of LFA-1. Our data suggest that Ndr2 activation is a crucial step to initiate TCR-mediated LFA-1 activation in T cells

    Spatially resolved star formation and inside-out quenching in the TNG50 simulation and 3D-HST observations

    Get PDF
    We compare the star-forming main sequence (SFMS) of galaxies – both integrated and resolved on 1 kpc scales – between the high-resolution TNG50 simulation of IllustrisTNG and observations from the 3D-HST slitless spectroscopic survey at z ∌ 1. Contrasting integrated star formation rates (SFRs), we find that the slope and normalization of the star-forming main sequence in TNG50 are quantitatively consistent with values derived by fitting observations from 3D-HST with the Prospector Bayesian inference framework. The previous offsets of 0.2–1 dex between observed and simulated main-sequence normalizations are resolved when using the updated masses and SFRs from Prospector. The scatter is generically smaller in TNG50 than in 3D-HST for more massive galaxies with M*> 1010 M⊙, by ∌10–40 per cent, after accounting for observational uncertainties. When comparing resolved star formation, we also find good agreement between TNG50 and 3D-HST: average specific star formation rate (sSFR) radial profiles of galaxies at all masses and radii below, on, and above the SFMS are similar in both normalization and shape. Most noteworthy, massive galaxies with M*> 1010.5 M⊙, which have fallen below the SFMS due to ongoing quenching, exhibit a clear central SFR suppression, in both TNG50 and 3D-HST. In contrast, the original Illustris simulation and a variant TNG run without black hole kinetic wind feedback, do not reproduce the central SFR profile suppression seen in data. In TNG, inside-out quenching is due to the supermassive black hole (SMBH) feedback model operating at low accretion rates
    • 

    corecore